Osseointegration: Making It Rightfor Patients with Amputations
1.7 million amputees currently living in the US.
185,000 amputations occur yearly in the US.
The wars in Afghanistan and Iraq have resulted in more than 450 new patients with amputations, including some with multiple amputations.
Transfemoral (above the knee) and transhumeral (above the elbow) amputees are currently an underserved population. Many are young, otherwise healthy individuals with amputations due to trauma or tumors. One-third of the amputee population has difficulty wearing a socket, often due to wounds, skin irritation, pain, or a short residual limb that cannot be easily fit with a standard external prosthesis.
The OPRA (Osseointegrated Prosthesis for the Rehabilitation of Amputees) is an implant system for direct anchorage of the external prosthesis to the skeleton, thereby bypassing the need for traditional sockets and making it right for patients with high amputations.
High level amputations adversely affect quality of life and productivity in society, often rendering affected individuals unable to work. This fact decreases the feasibility of participating or even taking the first step in joining our study.
Why is osseointegration important?
Despite improvements in socket fit and prosthetic design, individuals with high level amputations continue to have difficulty wearing a traditional socket. Some of the problems reported from wearing a traditional socket are perineal pressure, rotation and suspensory issues, skin breakdown, lack of stability, and general discomfort while walking.There are few options for these patients, and many must walk with crutches or a walker and sometimes are confined to a wheelchair.
How will osseointegration change people’s lives?
The use of the OPRA device in this patient population has the potential to provide a stable, durable anchor for prosthetic fitting, eliminating socket difficulties, and allowing an improved level of function, thereby making it right for these patients.
What we will do with the money?
We are currently the only center in the nation that provides this surgical and rehabilitative procedure. Apart from hospital expenses, patients traveling from across the nation will have to find resources to cover the cost of lodging and travel in order to have the first clinical screening, as well as surgery and aftercare. We will help to mitigate these costs for patients in financially disadvantaged situations.
Not all prosthetic costs are covered by the health insurance carriers. Some advanced external prosthetic components are quite expensive, placing them beyond the financial reach of many patients with amputations. This crowdsourcing effort will help meet such needs.
Basic, clinical, and translational research is expensive. UCSF will be the coordinating center for a multi-institutional study, partnering with colleagues such as the Walter Reed National Military Medical Center. Through our international Center for Osseointegration Research, Education, and Surgery (iCORES), we will work toward engineering, neuroscience, and robotic solutions for an ultimate goal of bidirectional, bionic volitional control of, and sensory feedback from, external prostheses so as to normalize hand function and gait for patients with amputations. Funds raised will be devoted to these research endeavors.
Our campaign has a modest short-term goal of $10,000 to ‘Make it Right’ for our amputee patients. Ultimately we would like to raise $50,000 allowing us to enroll up to 200 patients in the study at UCSF and Walter Reed combined over five years.
Choose a giving level
'Making it Right' with your support of the Osseointegration
Program with a $25 donation.